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Glutathione is a potent antioxidant that counteracts free radical damage and protects your body from stress, inflammation, or even toxin exposure. It’s made of the amino acids glycine, cysteine, and also glutamic acid in the liver [1]

In normal cells, glutathione is found in high levels (up to 5mM). However, this concentration may reduce with exposure to oxidative stress or age. Glutathione levels can be increased naturally through nutritious dietary intake. [2][3]

For instance, you may obtain glutathione from sulfur-rich foods (nuts or grains), green vegetables (asparagus, green beans, or spinach), or omega-3 sources such as fish [4]

However, some may struggle to consistently eat nutrients and foods to support glutathione levels. This is where the best organic glutathione supplements come in! Glutathione supplements are convenient and sustainable alternatives to maintain healthy glutathione levels in our bodies. 

Let’s have a closer look at the best glutathione supplements you can add to your cart today!

Quick Summary

Best For High Potency: Jarrow Formulas Glutathione Reduced

Ideal For Cost-Effectiveness: Now Foods Glutathione 

Best For Kosher-Friendly: Now Foods Glutathione  

Product NameGlutathione Content (mg)Price / Amount Direction To Use
BodyBio Liposomal Glutathione250~ $69 / 60 capsulesTake 1 capsule a day with or without food.
Now Foods Glutathione 500~ $14 / 30 capsulesTake 1 capsule daily, preferably on an empty stomach
DoubleWood S-Acetyl L-Glutathione100~ $30 / 60 capsulesTake 1-2 capsules per day with food.
NuBest White200~ $48 / 60 capsulesTake 1-2 capsules daily, as required, after meals 
Jarrow Formulas Glutathione Reduced500~ $57 / 120 capsulesTake 1 capsule per day with a meal.

Best Glutathione Supplements 

BodyBio Liposomal Glutathione

glutathione
GLUTATHIONE CONTENT (mg):

250

PRICE / AMOUNT:

~ $69 / 60 capsules

DIRECTION TO USE:

Take 1 capsule a day with or without food.

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Pros

  • Has 4.9-star ratings
  • Gluten-free
  • Non-GMO
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Cons

  • Expensive

BodyBio is a trusted family business that’s been up and running for 25 years now. Their sourced raw materials are of the highest quality and purity because they’re never oxidized or heat treated. 

Their liposomal glutathione supplement has a unique liposomal technology that assists in easy absorption. As a result, this is one of the best glutathione supplements in the USA in terms of efficacy, 

It acts as a powerful detoxification agent that helps remove harmful toxins like heavy metals or pesticides from our body system. Moreover, these capsules also help to support immune health and healthy aging.


Now Foods Glutathione 

glutathione
GLUTATHIONE CONTENT (mg):

500

PRICE / AMOUNT:

~ $14 / 30 capsules

DIRECTION TO USE:

Take 1 capsule daily, preferably on an empty stomach

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Pros

  • Ranked #2 in the L-Glutathione products category
  • Kosher Certified
  • GMP quality assured
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Cons

  • May cause disturbances in bowel movements 

This best organic glutathione supplement provides a holistic free radical neutralizer effect. This is because it’s co-formulated with other powerful antioxidants such as milk thistle extract and alpha lipoic acid. These ingredients work synergistically to facilitate healthy immune system functioning and proper detoxification processes. 

Besides, the fine quality of ingredients in this product ensures consumers benefit the most from this supplementation. This is evident in positive reviews claiming this product gives out “skin glowing” effects and reduces the appearance of cystic acne.


DoubleWood S-Acetyl L-Glutathione

glutathione
GLUTATHIONE CONTENT (mg):

100

PRICE / AMOUNT:

~ $30 / 60 capsules

DIRECTION TO USE:

Take 1-2 capsules per day with food or as recommended by your physician.

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Pros

  • Non-GMO
  • Manufactured in the USA 
  • Free of allergens such as soy and gluten 
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Cons

  • Some complaints of late shipping 

The addition of the S-Acetyl group to glutathione in this product improves the oral bioavailability of this supplementation. It’s mainly targeted to support optimal liver health and promote intracellular antioxidant activities. 

This glutathione supplement comes in easy-to-swallow vegetable capsules and has no unpleasant taste. Other than that, this product is third-party tested to meet its promised quality and safety standards. 


NuBest White

glutathione
GLUTATHIONE CONTENT (mg):

200

PRICE / AMOUNT:

~ $48 / 60 capsules

DIRECTION TO USE:

For faster results, take two capsules daily after meals. To maintain results after achieving desired skin, take one capsule daily after meals.

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Pros

  • Vegan
  • Made in an FDA-registered facility
  • Has long expiration dates of over two years
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Cons

  • May not work for some people, depending on skin type and color 

This best glutathione supplement for the skin contains an advanced blend of ingredients to support skin health from the inside. The glutathione, herb extracts, and vitamins in this supplement boost radiant and smoother skin texture. It’s a natural and nutrient-dense product that’s safe for daily use. 

Additionally, NuBest offers a 30-day money-back guarantee on all of its products. So if you’re unsatisfied with the product or simply changed your mind, you may request for a refund within 30 days of delivery.


Jarrow Formulas Glutathione Reduced

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GLUTATHIONE CONTENT (mg):

500

PRICE / AMOUNT:

~ $57 / 120 capsules

DIRECTION TO USE:

Take 1 capsule per day with a meal or as directed by your qualified healthcare professional.

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Pros

  • Suitable for vegans
  • Good and reliable packaging
  • Easy to swallow
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Cons

  • Contains magnesium stearate and silicon dioxide as an additive

Jarrow Formulas Glutathione Reduced is an intracellular antioxidant supplement that helps to “recycle” vitamin E and C in all types of tissues. Every capsule is formulated with pharmaceutical-grade glutathione to ensure you get the most benefits.  

Moreover, this product is non-GMO tested, and it contains no allergens, including soybeans, dairy, eggs, and more. It also comes in various packaging sizes (up to 120 capsules per bottle), conveniently providing a continuous supply to consumers.


Bottomline 

Glutathione is a highly beneficial antioxidant supplement that helps to combat free radicals and protect our bodily functions. It’s naturally produced in the body and must be maintained in healthy levels. Glutathione supplements are commercially marketed to boost immunity, improve physical performance and deliver anti-aging effects. 

Although there is paramount evidence of the efficacy of glutathione supplements, it may not be suitable for everyone. Therefore, you should consult your local healthcare provider before starting on any glutathione supplement.

FAQs

Yes. In a randomized, placebo-controlled study, sixty healthy female volunteers received oral supplementation of either placebo, reduced glutathione, or oxidized glutathione. At the end of this 12-week’s study, volunteers receiving oral glutathione of both forms demonstrated improvement in skin properties. 

For instance, oral glutathione supplementation in this study significantly reduced skin pigmentation and increased skin elasticity. No reports of major adverse effects occurred throughout the study [5].
The recommended glutathione dosage ranges from 500 to 1000 mg orally, daily in divided doses. However, consuming 1000 mg of glutathione daily is considered high and may not be suitable for everyone.  

The exact amount of glutathione you should take daily depends on many factors, including your age, sex, lifestyle, and health condition. Furthermore, taking too much glutathione can cause an overload of the antioxidant in the body, which can lead to unwanted side effects, including nausea, vomiting, heartburn, and abdominal pain  [6].

Disclaimer: This article is only a guide. It does not substitute the advice given by your own healthcare professional. Before making any health-related decision, consult your healthcare professional. We have assembled this article through in-depth research based on the information available at the date of publishing.  We may receive a small commission for purchases you make through our links, but this comes at NO extra cost to you. This commission allows us to continue doing what we love through Health Plugged, which is delivering evidence-based health information to our readers worldwide.

Editorial References And Fact-Checking

  1. Forman, H. J., Zhang, H., & Rinna, A. (2009). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696075/#:~:text=In%20most%20cells%20the%20GSH,can%20reach%20about%2010%20mM. 
  2. Minich, D. M., & Brown, B. I. (2019). A Review of Dietary (Phyto)Nutrients for Glutathione Support. Nutrients, 11(9), 2073. https://doi.org/10.3390/nu11092073
  3. S.C. Gad. AbstractGlutathione. (2014). Glutathione. Encyclopedia of Toxicology (Third Edition). Retrieved from https://www.sciencedirect.com/science/article/abs/pii/B9780123864543008502 
  4. Pizzorno J. (2014). Glutathione!. Integrative medicine (Encinitas, Calif.), 13(1), 8–12.
  5. Sinha, R., Sinha, I., Calcagnotto, A. et al. Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function. Eur J Clin Nutr 72, 105–111 (2018). https://doi.org/10.1038/ejcn.2017.132
  6. Weschawalit, S., Thongthip, S., Phutrakool, P., & Asawanonda, P. (2017). Glutathione and its antiaging and antimelanogenic effects. Clinical, Cosmetic and Investigational Dermatology, Volume 10, 147–153. https://doi.org/10.2147/ccid.s128339
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Irshika Suthakar, B.Pharm

Irshika is a Bachelor of Pharmacy (B.Pharm) graduate who enjoys crafting in-depth health and wellness content. Her experience interacting with real-life patients during work has enabled her to pick up valuable communication skills, which translates into well-written and highly-engaging content for her readers. Being a health content writer is what she considers a huge privilege because she loves empowering people to make informed health choices. LinkedIn

Authors

  • Irshika is a Bachelor of Pharmacy (B.Pharm) graduate who enjoys crafting in-depth health and wellness content. Her experience interacting with real-life patients during work has enabled her to pick up valuable communication skills, which translates into well-written and highly-engaging content for her readers. Being a health content writer is what she considers a huge privilege because she loves empowering people to make informed health choices. LinkedIn

  • Kim is a Registered Nurse and has been a medical freelance writer for more than six years. Starting off as a writer, Kim moved to proofreading and editing all the articles posted on HealthPlugged. She’s an enthusiast for health and wellness, being one to keep herself fit and adventurous for outdoor activities. LinkedIn

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Irshika is a Bachelor of Pharmacy (B.Pharm) graduate who enjoys crafting in-depth health and wellness content. Her experience interacting with real-life patients during work has enabled her to pick up valuable communication skills, which translates into well-written and highly-engaging content for her readers. Being a health content writer is what she considers a huge privilege because she loves empowering people to make informed health choices. LinkedIn