Probiotics have long been popular in the market because of their scientifically-proven benefits in promoting a healthy gut and enhancing immunity. 

Taking probiotics is not a new concept, especially among the health-conscious. Those who are interested in practicing a healthy lifestyle would consider probiotics as one of the essentials.

But there is more to probiotics than just regulating the good bacteria in the gut. It has other documented effects on the different body systems that have become topics of interest in recent studies.

The lesser-known sex-specific benefits of probiotics are the relatively newer indications among its consumers. Both men and women now have more reasons to include probiotics in their daily regimen.

In this article, we will focus on the potential benefits of taking probiotics among men and the helpful ways to optimize their effects.

What are Probiotics?

The World Health Organization defines probiotics as “live microorganisms, which, when administered in adequate amounts, confer a health benefit on the host”.

Intestinal microbes that modify the gut flora to enhance overall health are identified and selected as probiotics. The most widely used species in manufacturing probiotic food products and dietary supplements belong to the genera Lactobacillus and Bifidobacterium.

Although the complete description of what probiotics do in the body has not yet been fully elucidated, there have been notable findings in past studies. 

Microbiologists have reported that the “good” bacteria in probiotics have antioxidant and anti-inflammatory properties that help regain and sustain the balance within the body after disruption by an illness.

Several probiotic studies have continuously provided convincing evidence of its potential consumer advantages. Because of this, the demand for products derived from probiotics has also significantly increased.

This resulted in probiotics being marketed in various forms to fit the preference of every consumer type. Currently, probiotics are available in fermented foods, such as yogurts, kimchi, and sauerkraut, as well as in capsules, liquids, and powders preparation. [1][2][3]

Benefits of Probiotics for Men

Source: Canva

In addition to the frequently-studied helpful effects of probiotics, such as bowel disease prevention, immune system enhancement, lactose intolerance control, intestinal microbial balance, and traveler’s diarrhea therapy. Several investigative studies have reported new discoveries of its potential effects on systems outside of the gastrointestinal realm.

Probiotics are purported to have benefits for improving testosterone levels and overall male fertility.

Studies about reproductive health have elaborated that one of the most common reasons for male infertility is the excessive production of free radicals in the sperm cells coupled with reduced antioxidant activity responsible for removing the free radicals. This combination led to a decrease in sperm quality.

Free radicals are the unintended products of cellular metabolism. They are harmful molecules because of their highly reactive and unstable nature. If the body fails to “clean up” these waste products, their accumulation may damage other molecules within the cell, such as DNA and other proteins, resulting in cellular dysfunction.

Fortunately, probiotic supplementation can help improve the quality of semen characteristics because of its antioxidant property. In one study, it was noted that with continuous intake of probiotics for 10 weeks, the following were observed: [4][5][6]

  • Increased ejaculate volume
  • Increased total sperm count
  • Adequate sperm concentration
  • Improved sperm motility
  • Better sperm cell viability
  • Reduced serum inflammatory markers
  • Increased serum testosterone levels

Side Effects of Probiotics for Men

Probiotics are categorized as dietary supplements that do not require FDA approval before being sold in the market. For this reason, probiotics lack reliable information on the frequency and severity of side effects.

However, according to several studies, probiotics have an extensive history of apparently safe use, particularly in healthy people. For high-risk individuals, such as those with severe illnesses or compromised immune systems, it is advisable to consult with a healthcare provider before consuming any probiotic product. [7]


Probiotics are live microorganisms known to improve gut health when ingested in adequate amounts. Intake of probiotic supplements has been linked to many health benefits, mainly involving the gastrointestinal and immune systems.

In the gut, probiotics regulate the local immunity and maintain the balance of intestinal flora, especially after a disease. It also can eliminate harmful pathogens by promoting good bacteria colonization and producing inhibitors, such as bactericides and organic acid.

However, probiotics have more functions than their known applications in the gut. It also extends its advantages in alleviating common male fertility problems. 

Studies have shown that continuous and adequate intake of probiotics can significantly increase sperm concentration, count, and mobility among male consumers.


Since probiotics are not FDA-approved, they did not undergo clinical trials to determine their efficacy. Hence, there are no existing general guidelines about the recommended dose of probiotics to be consumed to achieve a beneficial effect.

But in one study that demonstrated the sperm quality-enhancing effects of probiotics among male subjects with fertility issues, the researchers used the 500mg capsule preparation.
Yes, probiotics are generally safe and recommended to be taken daily. The studies that have elaborated on the male-specific benefits of probiotics noted improved semen characteristics among men who took probiotic supplements daily for 6 weeks, minimum.
Yes. A few studies have reported that certain probiotic strains can increase the absorption of key nutrients, such as amino acids from protein-rich food, contributing to increased muscle synthesis and physiology.

Also, the intake of probiotic strains with known anti-inflammatory effects has been observed to improve recovery from muscle-damaging exercise.

Disclaimer: This article is only a guide. It does not substitute the advice given by your healthcare professional. Before making any health-related decision, consult your healthcare professional.

Editorial References And Fact-Checking

  1. Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D. J., Pot, B., Morelli, L., Canani, R. B., Flint, H. J., Salminen, S., Calder, P. C., & Sanders, M. E. (2014). Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature reviews. Gastroenterology & hepatology, 11(8), 506–514.
  2. Shahrokhi M, Nagalli S. Probiotics. [Updated 2023 Mar 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:
  3. Shi, L. H., Balakrishnan, K., Thiagarajah, K., Mohd Ismail, N. I., & Yin, O. S. (2016). Beneficial Properties of Probiotics. Tropical life sciences research, 27(2), 73–90.
  4. Helli, B., Kavianpour, M., Ghaedi, E., Dadfar, M., & Haghighian, H. K. (2022). Probiotic effects on sperm parameters, oxidative stress index, inflammatory factors and sex hormones in infertile men. Human fertility (Cambridge, England), 25(3), 499–507.
  5. Valcarce, D. G., Genovés, S., Riesco, M. F., Martorell, P., Herráez, M. P., Ramón, D., & Robles, V. (2017). Probiotic administration improves sperm quality in asthenozoospermic human donors. Beneficial microbes, 8(2), 193–206.
  6. Wang, H. et al. (2022) The Microbiome, an Important Factor That Is Easily Overlooked in Male Infertility. Frontiers in Microbiology. Section Infectious Agent and Disease. Vol 13.
  7. Probiotics: What You Need to Know. 2023. National Center for Complementary and Integrative Health. National Institutes of Health.


  • Dr. Kara Marcella Barro, M.D.

    Dr. Kara Marcella Barro is a licensed physician who has been serving as a General Practitioner at her local health center. She has devoted her skills and knowledge as a public health doctor to serve the poor and marginalized. At the same time, she is also an educator who passionately promotes preventive medicine through her lectures and writing in the hopes of a better health outcome for everyone. LinkedIn


Dr. Kara Marcella Barro is a licensed physician who has been serving as a General Practitioner at her local health center. She has devoted her skills and knowledge as a public health doctor to serve the poor and marginalized. At the same time, she is also an educator who passionately promotes preventive medicine through her lectures and writing in the hopes of a better health outcome for everyone. LinkedIn