5 Best Pterostilbene Supplements (2023)

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Pterostilbene is a natural substance and non-toxic polyphenol that occurs in plants in small quantities. Blueberries have the richest amount of pterostilbene, but that amount is still lower than what is found in dietary supplements.

If you’re looking for the best pterostilbene supplements on the market, we’ve got your back! We’ll cover some of the top brands you can get your hands on.

Quick Summary

Best Added Value: Dr. Mercola Quercetin and Pterostilbene Advanced

Lowest Price: Jarrow Formulas, Trans-Pterostilbene

Best Rated/Most Reviewed: Double Wood Pterostilbene

5 Best Pterostilbene Supplements (2023)

There are a lot of pterostilbene supplements available in the market, and it can be daunting to look through dozens of them. Well, we’ve chosen the top 5 best pterostilbene supplements based on our research.

Jarrow Formulas, Trans-Pterostilbene

PTEROSTILBENE CONTENT:

50 mg

PRICE / NUMBER OF CAPSULES:

$19.17/60

DOSAGE RECOMMENDATION:

Take 1 capsule daily

The Jarrow Trans-Pterostilbene is vegan safe since the brand uses veggie caps for the capsules. Each capsule contains 50 mg of trans-pterostilbene, which is a calorie-restriction mimetic. Jarrow Formulas tests each product for purity and potency to ensure quality.

The brand uses Silbinol, which is pterostilbene that is extracted from the heartwood of Indian Kino. The capsules contain antioxidants and support healthy aging through the use of Silbinol, which regulates gene expression and energy metabolism.  A few side effects, such as light-headedness and numbness, were reported. In general, the reviews are great with many saying they feel an increase in energy and clear-mindedness.

Dr. Mercola Quercetin and Pterostilbene Advanced

PTEROSTILBENE CONTENT:

50 mg

PRICE / NUMBER OF CAPSULES:

$33.97/60

DOSAGE RECOMMENDATION:

Take 2 capsules daily. One in the morning and one in the evening

Dr. Mercola is a trusted brand that is known for using quality ingredients in its supplements. Aside from pterostilbene, the capsules also contain 500 mg of quercetin which is found in many plants. Quercetin contains antioxidant and anti-inflammatory properties that may aid in controlling blood sugar and reducing swelling amongst other benefits. Essentially, it enhances the benefits that pterostilbene already provides.

The reviews for this product are great, and it has garnered 4.8 stars out of 5 in iHerb from 119 ratings. Some users have commended it for being a great immune booster that has helped them through the pandemic. It also worked well with reducing the swelling of the eyes and nose. However, some raised their concerns regarding the use of maltodextrin, which is an artificial additive. The brand clarified on Amazon that the source of the maltodextrin used is from potatoes instead of corn, and is used as a binder and flow agent for the capsules.

Double Wood Pterostilbene

PTEROSTILBENE CONTENT:

100 mg

PRICE / NUMBER OF CAPSULES:

$19.95/60

DOSAGE RECOMMENDATION:

Take 100 mg capsule once or twice daily

This pterostilbene supplement is made in a GMP-certified facility that ensures that the highest quality product is manufactured. It was also third-party tested for transparency of the ingredients used. Each capsule contains 100 mg of pterostilbene, and the dosage recommended by the brand is to take 1 capsule once or twice daily. However, the brand states that you can take 200 to 400 mg daily to aid in the reduction of glucose and cholesterol.

Double Wood Pterostilbene promotes cardiovascular health through potent antioxidants. It may also support cognitive function and aid in maintaining healthy blood sugar levels. Customer reviews are great with 4.6 stars out of 5 on Amazon from 1,174 ratings. Some commented that it lowered their blood pressure and increased their energy levels and concentration. However, some reported having headaches and increased LDL cholesterol levels.

Source Naturals Pterostilbene

PTEROSTILBENE CONTENT:

50 mg

PRICE / NUMBER OF CAPSULES:

$20.65/60, $40.25/120

DOSAGE RECOMMENDATION:

Take 1 capsule daily

Each capsule from this supplement contains 50 mg of pTeroPure pterostilbene. It contains anti-aging compounds that have the same structure as resveratrol. It is made by a trusted brand that is committed to providing high-quality supplements with its well-researched formulas and the inclusion of the most bioavailable forms of nutrients.

Not a lot of customer reviews are available on the brand website or Amazon. For the few that are available, users said that the supplement is a good addition to their anti-aging routine or diet. Some also commended the high quality of the product that has increased their energy.

Super Smart Pterostilbene Supplement

PTEROSTILBENE CONTENT:

100 mg

PRICE / NUMBER OF CAPSULES:

$39.00/30

DOSAGE RECOMMENDATION:

Take 1-2 capsules daily

The company gives very detailed research and details on their website for transparency. Directions to use, side effects, and benefits of pterostilbene are included with linked studies to guide possible customers regarding its product. 

Each pterostilbene capsule contains 100 mg of pTeroPure with a purity of 99%. The supplement has anti-aging properties with high bioavailability compared to other dietary supplements. It protects the immune system as well as provides anti-inflammatory properties and antioxidants.

What Are The Benefits Of Pterostilbene?

Pterostilbene has numerous health and wellness benefits, including being a powerful antioxidant that can aid in weight loss as it reduces oxidative stress. [1] In addition, it may be able to normalize blood sugar, which would be beneficial to diabetics and prevent insulin resistance in cells. Its bioavailability is at 80%,  meaning that the body absorbs it better as it passes through cell membranes more easily. [2] 

The pterostilbene supplements can also slow down the aging process alone or by being combined with NMN (nicotinamide mononucleotide). The NMN is also important to the formation of NAD+ which is an enzyme vital to every cell of the body. Other benefits include providing anti-inflammatory properties, improving cognitive functions, and maintaining brain health.

How to Choose the Best Pterostilbene Supplement

When choosing the right supplements, you’ll need to consider a few things. Your choice can either help you achieve your goals or give you health complications. Here are a few things to consider before you choose the right one for you:

Dosage Recommendation

Be mindful of the pterostilbene dosage in whatever brand you choose. The recommended dosage, based on studies, is 250mg daily. Consuming more can have adverse results, so be sure to check the pterostilbene content per capsule when you choose a supplement. Your weight can also be a factor in how much you can take. It’s also best to consult a healthcare professional beforehand.

Product Purity

Choose a supplement that has a clear list of ingredients. A lot of supplements are manufactured with co-formulated ingredients. Read what is listed on packaging to ensure that you’ll be consuming something of quality. A lot of supplements have artificial flavorings, binders, fillers, and preservatives. Those can trigger allergic reactions or affect your other medications.

Trusted Brand

This is important when you’re considering consuming supplements for the long haul. Choose a brand that practices transparency to avoid potential side effects. A lot of brands lie about their ingredients or the percentage of substance content they use to deceive customers. So, be cautious and read about the brand to know their process. 

User Reviews

Many of these supplements have customer reviews demonstrating the product’s efficacy and quality. It’s best to look through some previous user reviews to gauge if the product is high-quality. You may also find information on the taste and size of the capsules, which may be helpful.

Possible Side Effects of Pterostilbene Supplements

Studies on pterostilbene supplements are still lacking in clinical trials. Most research is from cell or animal studies. Hence, precautions should be practiced when looking for the best pterostilbene supplements. Some studies showed that there was an increase in LDL cholesterol when participants took pterostilbene. [3] However, those taking the recommended dosage daily of 250mg reported no side effects.

Another thing to remember is that there are currently no studies available involving pregnant or breastfeeding women. Nonetheless, since pterostilbene can be consumed by eating fruits that contain it, it’s generally safe to ingest in small amounts. You can consult a doctor just to be on the safe side. Also, you should read product or FDA disclaimers before buying.

Frequently Asked Questions (FAQ)

What Does Pterostilbene do for the Body?

Pterostilbene provides a lot of benefits, such as activating sirtuins which help to slow down the damage that takes place as one grows older. [4] It also aids in maintaining good heart health, controlling blood sugar, and may aid in preventing cancer progression among other health benefits. However, more human studies need to be conducted.

Which is Better? Is Pterostilbene Better than Resveratrol?

Resveratrol is found in the skin of red grapes, red wine, and berries. It provides almost the same benefits as pterostilbene, which is why brands have capitalized on it by selling resveratrol supplements. However, the main difference is bioavailability. Pterostilbene has 80% while resveratrol only has 20%. Bioavailability refers to the amount of substance that actually goes into your system.

Is Pterostilbene Good for the Brain?

Yes, according to studies and customers of pterostilbene supplements. The substance aids in improving cognitive and healthy motor functions. Research is currently conducted to study its impact in protecting the brain from diseases such as Alzheimer’s disease. [5] Users also noted an increase in their memory functions and alertness as well as calmness.

Does Pterostilbene Increase LDL?

Yes, it does. According to studies, participants who took pterostilbene supplements experienced an increase in their LDL cholesterols. Some user reviews have also noted increased LDL cholesterol. However, taking it within the recommended dose lowers the risk of any side effects. 

Bottomline: Best Pterostilbene Supplements

Pterostilbene is naturally present in some fruits, particularly berries, but brands have begun producing pterostilbene supplements to gain from its numerous benefits. So far, more human studies need to be conducted to conclude the long-term impact of the substance on the overall health of the body. Deciding what the best pterostilbene supplement is for you can be time-consuming, but choosing the right one can improve your health in the long haul.

Disclaimer: This article is only a guide. It does not substitute the advice given by your own healthcare professional. Before making any health-related decision, consult your healthcare professional. We have assembled this article through in-depth research based on the information available at the date of publishing.  We may receive a small commission for purchases you make through our links, but this comes at NO extra cost to you. This commission allows us to continue doing what we love through Health Plugged, which is delivering evidence-based health information to our readers worldwide.

Editorial References And Fact-Checking

• McCormack, D., & McFadden, D. (2013). A review of pterostilbene antioxidant activity and disease modification. Oxidative medicine and cellular longevity, 2013, 575482. https://doi.org/10.1155/2013/575482
• Kapetanovic, I. M., Muzzio, M., Huang, Z., Thompson, T. N., & McCormick, D. L. (2011). Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer chemotherapy and pharmacology, 68(3), 593–601. https://doi.org/10.1007/s00280-010-1525-4
• Riche, D. M., Riche, K. D., Blackshear, C. T., McEwen, C. L., Sherman, J. J., Wofford, M. R., & Griswold, M. E. (2014). Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial. Evidence-based complementary and alternative medicine : eCAM, 2014, 459165. https://doi.org/10.1155/2014/459165
• Yuan, Y., Cruzat, V. F., Newsholme, P., Cheng, J., Chen, Y., & Lu, Y. (2016). Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis. Mechanisms of ageing and development, 155, 10–21. https://doi.org/10.1016/j.mad.2016.02.003
• Chang, J., Rimando, A., Pallas, M., Camins, A., Porquet, D., Reeves, J., Shukitt-Hale, B., Smith, M. A., Joseph, J. A., & Casadesus, G. (2012, September). Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer’s disease. Neurobiology of Aging, 33(9), 2062–2071. https://doi.org/10.1016/j.neurobiolaging.2011.08.015