Dave Asprey, often called the “Father of Biohacking,” has been prominent in the health and wellness industry for years. Known for his Bulletproof Coffee and dedication to optimizing human performance, Asprey has introduced a range of supplements that promise to enhance various aspects of health. 

But what are these supplements, and what benefits do they offer? Let’s dive in. 

Dave Asprey Supplements List

Dave Asprey
Source: Pexels

Want to know the supplements that Dave Asprey takes? Here are some of the supplements:

1. Bulletproof Brain Octane Oil:

Dave Asprey
Source: Canva

Brain Octane Oil, one of the flagship products of Dave Asprey’s Bulletproof brand, is a type of MCT (Medium Chain Triglyceride) oil. MCTs are a unique type of fat, metabolized differently than other fats. The substances are not stored. Instead, they are quickly converted into ketones, which the brain and body can use as an energy source.

Brain Octane Oil is derived from 100% pure coconut oil. It is designed to produce ketones, molecules that provide energy for the brain and body without relying on glucose from carbohydrates or sugar. [1]  


Several studies have shown the potential benefits of MCTs. 

  1. Weight Management: Leptin and peptide YY, two hormones that help the body feel full, are released more often when MCTs are consumed. [5

As a result of feeling full, individuals may consume less food than they need or want. Consequently, reducing appetite may aid in weight management.

  1. Energy and Endurance: Athletes have reported improved performance when incorporating MCTs into their diets. A study found that those who took MCTs during moderate and high-intensity exercise had lower lactate levels, contributing to fatigue.
  2. Brain Health: Ketones produced from MCTs provide an alternative energy source for the brain. Research has suggested they might benefit brain disorders like epilepsy and Alzheimer’s. [6]

2. Bulletproof Collagen Protein: 

Dave Asprey
Source: Canva

Collagen production in our bodies naturally declines as we get older. This supplement replenishes the body’s collagen levels, supporting skin health, joint flexibility, and overall bone strength. [2

It is sourced from pasture-raised cows, ensuring a high-quality product.


Supplementing with collagen has been shown to:

  1. Improve Skin Health: A study found that women who took collagen supplements for eight weeks had better-hydrated skin and significantly reduced wrinkle depth. [7]
  2. Support Joint Health: Cartilage, the tissue that resembles rubber and protects joints, is kept in good shape by collagen. According to research, athletes who used collagen supplements had reduced joint discomfort. [8]
  3. Bone Health: Collagen gives bones structure and keeps them strong. Some studies suggest collagen supplements reduce the risk of bone disorders such as osteoporosis. [9]

3. Bulletproof Glutathione Force: 

Dave Asprey
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Glutathione is often termed the body’s “master antioxidant.” It plays a crucial role in detoxifying the body and protecting cells from oxidative stress. This supplement ensures that glutathione is effectively absorbed, supporting liver health and overall cellular function.


Research has shown that glutathione:

  1. Supports Liver Function: The liver is the primary organ in the body responsible for detoxification, and glutathione plays a vital role in this process.
  2. Boosts Immune Health: Glutathione is a substance that helps white blood cells work properly. White blood cells are important for fighting off infection and disease.
  3. Anti-Aging Properties: By combating oxidative stress, glutathione can slow aging.  [10]

4. Bulletproof Sleep Mode: Ensuring Restful Nights

Dave Asprey
Source: Canva

Quality sleep is foundational for overall health. The Sleep Mode supplement, introduced by Dave Asprey, contains ingredients, including melatonin, to support the body’s natural sleep cycle and promote restful, rejuvenating sleep. [3]


  • Deep and Restorative Sleep: This supplement aids in achieving deeper sleep cycles, allowing the body and mind to rejuvenate fully.
  • Cognitive Function: A good night’s sleep is crucial for optimal brain function. Regular intake can lead to improved focus, memory, and decision-making.
  • Mood Regulation: Sleep has a direct impact on our mood. With better sleep quality, one can expect a more stable and positive attitude throughout the day.
  • Physical Health: Sound sleep is vital in healing and repairing the heart and blood vessels, reducing the risk of chronic diseases.
  • Stress Reduction: Achieving deep sleep can help reduce stress and anxiety levels, promoting a sense of calm.
  • Immune System Boost: Adequate sleep supports the immune system, making the body more resilient to infections.
  • Balanced Hormone Levels: Sleep influences the balance of several hormones in the body, including insulin, cortisol, and growth hormones.

What Anti-Aging Supplements Does Dave Asprey Take?

Dave Asprey
Source: Canva

Dave Asprey’s approach to anti-aging is holistic, focusing on cellular health, mitochondrial function, and reducing oxidative stress. Some of the supplements he has discussed in his podcasts and blogs include:

  1. NAD+: A coenzyme that is essential for maintaining cellular health and generating energy. It is believed to aid in DNA repair and increase lifespan.
  2. Resveratrol: Resveratrol is a polyphenol found in the skin of red grapes. It has antioxidant properties that have been linked to a reduced risk of heart disease and a longer lifespan. It is believed to activate specific pathways in the body that protect against age-related diseases.
  3. PQQ: This compound supports mitochondrial health. Mitochondria, the powerhouses of our cells, play a vital role in energy production and overall vitality. [4]

The Bottomline

Dave Asprey’s supplements are deeply rooted in scientific research, enhancing multiple well-being aspects. Numerous people have shared positive experiences after using these supplements. 

However, it’s important to understand that everyone’s body is unique, and reactions can differ.   Before introducing any new supplements into your regimen, it is always advisable to see a healthcare professional, for the best results and safety,


Dave Asprey founded Bulletproof, a brand focusing on dietary supplements, coffee, and wellness products.
Biohacking is making lifestyle changes to hack the body’s biology and optimize health and performance.
Dietary supplements are not FDA-approved but must comply with FDA regulations for safety and labeling.
It is essential to adhere to the dose stated on the product label or seek medical advice.
While you can take many supplements together, consult a healthcare professional to ensure no interactions.

Disclaimer: This article is only a guide. It does not substitute the advice given by your healthcare professional. Before making any health-related decision, consult your healthcare professional.

Editorial References And Fact-Checking

  1. Nafar, F., Clarke, J. P., & Mearow, K. M. (2017). Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways. Neurochemistry international, 105, 64–79. https://doi.org/10.1016/j.neuint.2017.01.008
  2. Barati, M., Jabbari, M., Navekar, R., Farahmand, F., Zeinalian, R., Salehi-Sahlabadi, A., Abbaszadeh, N., Mokari-Yamchi, A., & Davoodi, S. H. (2020). Collagen supplementation for skin health: A mechanistic systematic review. Journal of cosmetic dermatology, 19(11), 2820–2829. https://doi.org/10.1111/jocd.13435
  3. Xie, Z., Chen, F., Li, W. A., Geng, X., Li, C., Meng, X., Feng, Y., Liu, W., & Yu, F. (2017). A review of sleep disorders and melatonin. Neurological research, 39(6), 559–565. https://doi.org/10.1080/01616412.2017.1315864
  4. Itoh, Y., Hine, K., Miura, H., Uetake, T., Nakano, M., Takemura, N., & Sakatani, K. (2016). Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ™) on Cognitive Functions. Advances in experimental medicine and biology, 876, 319–325. https://doi.org/10.1007/978-1-4939-3023-4_40 
  5. Mumme, K., & Stonehouse, W. (2015). Effects of medium-chain triglycerides on weight loss and body composition: a meta-analysis of randomized controlled trials. Journal of the Academy of Nutrition and Dietetics, 115(2), 249–263. https://doi.org/10.1016/j.jand.2014.10.022
  6. Takeishi, J., Tatewaki, Y., Nakase, T., Takano, Y., Tomita, N., Yamamoto, S., Mutoh, T., & Taki, Y. (2021). Alzheimer’s Disease and Type 2 Diabetes Mellitus: The Use of MCT Oil and a Ketogenic Diet. International journal of molecular sciences, 22(22), 12310. https://doi.org/10.3390/ijms222212310
  7. Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin pharmacology and physiology, 27(1), 47–55. https://doi.org/10.1159/000351376
  8. Khatri, M., Naughton, R. J., Clifford, T., Harper, L. D., & Corr, L. (2021). The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review. Amino acids, 53(10), 1493–1506. https://doi.org/10.1007/s00726-021-03072-x
  9. Figueres Juher, T., & Basés Pérez, E. (2015). REVISIÓN DE LOS EFECTOS BENEFICIOSOS DE LA INGESTA DE COLÁGENO HIDROLIZADO SOBRE LA SALUD OSTEOARTICULAR Y EL ENVEJECIMIENTO DÉRMICO [An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing]. Nutricion hospitalaria, 32 Suppl 1, 62–66. https://doi.org/10.3305/nh.2015.32.sup1.9482
  10. Homma, T., & Fujii, J. (2015). Application of Glutathione as Anti-Oxidative and Anti-Aging Drugs. Current drug metabolism, 16(7), 560–571. https://doi.org/10.2174/1389200216666151015114515
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Farah Jassawalla

Farah is a veteran writer, season journalist, and copywriting expert with over six years of professional experience in the content creation field. Her forte lies in translating medical jargon and complicated health terms into easy-to-understand language for readers who may not have a medical background. LinkedIn


  • Farah is a veteran writer, season journalist, and copywriting expert with over six years of professional experience in the content creation field. Her forte lies in translating medical jargon and complicated health terms into easy-to-understand language for readers who may not have a medical background. LinkedIn

  • Kim is a Registered Nurse and has been a medical freelance writer for more than six years. Starting off as a writer, Kim moved to proofreading and editing all the articles posted on HealthPlugged. She’s an enthusiast for health and wellness, being one to keep herself fit and adventurous for outdoor activities. LinkedIn


Farah is a veteran writer, season journalist, and copywriting expert with over six years of professional experience in the content creation field. Her forte lies in translating medical jargon and complicated health terms into easy-to-understand language for readers who may not have a medical background. LinkedIn