Pregnenolone is a chemical found in our bodies that acts as a pro-hormone and synthesizes in the brain and other organs. It ensures the proper production of hormones like DHEA, progesterone, cortisol, and testosterone. The right amount of these hormones promotes a healthy lifestyle. 

Since it induces progesterone production, women benefit from it. However, research shows men can also benefit from this biochemical precursor to testosterone. 

Pregnenolone Benefits For Men

Pregnenolone can be highly beneficial in improving men’s health by protecting them against various health conditions. Here are some benefits pregnenolone has on male health:

Boosts Testosterone Levels 

The key to men’s health is testosterone. A lack of testosterone can lead to issues such as emotional imbalance, lack of sex drive, and slow muscular growth. You can add pregnenolone supplements to your diet to stabilize testosterone production levels. 

Since pregnenolone is a precursor hormone, consuming it produces sex hormones like DHT and testosterone in the body. DHT and testosterone increase libido and sex drive in men. However, research in this field is limited, and further study is required to prove the results.

Improves Memory and Spatial Perception

Pregnenolone enhances brain function, which as a result, improves mental clarity and memory. A report published in 2001 showed that pregnenolone impacted animal memory. However, there is little research data on humans. [1]

Some evidence also states that steroid hormones improve spatial perception, where you can see the size of an object and know the distance from it while moving toward or away from it. 

Helps Treat Mild Depression

According to an animal-based study in 2012, pregnenolone can help reduce depression as well. Research showed that the chemical treated certain abnormalities in brain cells. Other studies also showed that people facing depression had extremely low levels of pregnenolone in their bodies. 

People consuming a certain dosage have noticed a change in their demeanor and said it improved their depressive state. 

Eases Fatigue

Since pregnenolone acts as a precursor hormone to other hormones in the body, it is also directly related to daily stress. Consuming pregnenolone will help you feel energetic throughout the day, and you’ll also be able to focus on your tasks better. 

Treats Schizophrenia  

As per a report published in 2011, pregnenolone promises successful results in treating schizophrenia in people. Intake of this hormone affects steroid compounds in the brain and increases gamma-aminobutyric acid levels. [2]

Pregnenolone Side Effects on Men

Consuming any supplement in large quantities can have side effects on the body. However, due to a lack of research on the hormone and its supplements, there is little knowledge about the side effects it may cause. 

Pregnenolone is safe for consumption for 12 weeks if you don’t have any serious underlying health conditions. Some noted minor side effects include rashes, acne, hair loss, stomach issues, trouble sleeping, sweating, agitation, and tremors. It also increases estradiol levels which causes estrogen to rise in the body. 

Pregnenolone may also cause an abnormal heartbeat, muscle pain, or a change in appetite. There is insufficient research to determine whether pregnenolone is safe to use after 12 weeks of consumption or not. [3]

Pregnenolone Bodybuilding

Many bodybuilding supplements have pregnenolone as a part of the ingredients since it is a perfect mix of anti-inflammatory and muscle-healing properties. The hormone also helps in reducing body sores and fatigue. Including it in your daily regimen will help you build stamina and make workouts easier. You should consume it in your pre-workout intake for the best results. 

How Long Does it Take For Pregnenolone to Take Effect

Pregnenolone is not suggested for more than 12 weeks. Consuming supplements takes time to show results, so expect the best results to show after 3 to 4 months of daily intake. 

Pregnenolone Dosage For Sleep

Since pregnenolone decreases stress and fatigue, it is also great for inducing sleep. While medical professionals don’t advise a universal dosage, be sure to read the product label on the supplement you consume. Normally, the dosage for pregnenolone for sleep is 30mg. 

How Much Pregnenolone Should Men Take?

The advised dosage of pregnenolone for men is 30mg daily. Higher dosage is only advised by a healthcare professional. Otherwise, it can be too dangerous. 

What Does Pregnenolone Do For Men?

Pregnenolone acts as a precursor hormone in the body. It helps produce hormones such as DHEA, cortisol, estrogen, and testosterone. It boosts testosterone production in the body for men, increasing libido and sex drive. 

Moreover, men interested in bodybuilding can also use pregnenolone to boost stamina and increase endurance. Pregnenolone also helps reduce muscular pain and cramps caused by muscle buildup exercises. 

Does Pregnenolone Increase Testosterone?

Pregnenolone is a precursor hormone that increases the production of hormones in the body, particularly testosterone. Men who have a low libido normally take pregnenolone to increase testosterone levels. 

Bottomline: Pregnenolone Benefits for Men

Pregnenolone is a steroid hormone that has multiple benefits, especially for men. Not only does it boost hormone production in the body, but it also helps the brain to function better. However, you should consume it cautiously since a high intake of pregnenolone is harmful. Furthermore, more research is required to establish how much dosage should be consumed for results to appear. 

Disclaimer: This article is only a guide. It does not substitute the advice given by your healthcare professional. Before making any health-related decision, consult your healthcare professional.

Editorial References And Fact-Checking

  • Vallée, M., Mayo, W., & Le Moal, M. (2001). Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging. Brain research. Brain research reviews, 37(1-3), 301–312.
  • Marx, C. E., Bradford, D. W., Hamer, R. M., Naylor, J. C., Allen, T. B., Lieberman, J. A., Strauss, J. L., & Kilts, J. D. (2011). Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence. Neuroscience, 191, 78–90.
  • PREGNENOLONE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews. (n.d.).


  • Farah Jassawalla

    Farah is a veteran writer, season journalist, and copywriting expert with over six years of professional experience in the content creation field. Her forte lies in translating medical jargon and complicated health terms into easy-to-understand language for readers who may not have a medical background. LinkedIn


Farah is a veteran writer, season journalist, and copywriting expert with over six years of professional experience in the content creation field. Her forte lies in translating medical jargon and complicated health terms into easy-to-understand language for readers who may not have a medical background. LinkedIn