Supplementation with vitamin D3 and K2 confers not only the benefits that are normally associated with vitamin D and vitamin K but also additional advantages to one’s health that can only be gained by taking these two vitamins together.
Table of Contents
Vitamin D3, also known as cholecalciferol, is a fat-soluble vitamin that primarily increases intestinal calcium and phosphate absorption.
Benefits Of Vitamin D3
It is needed for
- Absorption of intestinal calcium
- Absorption of intestinal phosphorus
- Building bones and keeping them strong
- Improving mood
- Boosting immunity
- Reducing inflammation
- Improving heart function
Menaquinone, or vitamin K2, is one of the three vitamin K. Most people are unfamiliar with vitamin K2. This vitamin is uncommon in the Western diet and has received little attention from the general public.
Nonetheless, this potent nutrient is crucial for many aspects of your health. Some believe that vitamin K2 is the missing link between diet and several chronic diseases.
Benefits Of Vitamin K2
It contributes to
- Skin health
- Bone metabolism
- Proper brain function
- Preventing heart-related diseases
Its primary function is to regulate calcium metabolism. It aids in bone formation and inhibits blood vessel calcification.
Vitamin D3 and Vitamin K2 In Combination
- Building bones
- Maximizing bone strength
- Inhibiting blood vessel calcification
Thus, if we want calcium to be utilized entirely in our body, we need both the vitamins D3 and K2.
How do they work?
The active form of Vitamin D3 (cholecalciferol) is required for intestinal calcium absorption. Without Vitamin D3’s active form, the calcium in our diet would be wasted.
After calcium is absorbed from the intestine into the blood, we want it to be deposited in our bones, which is when Vitamin K2 is required. Osteocalcin is activated by vitamin K2 ( a protein necessary for depositing calcium into the bones). Vitamin K2 also activates matrix GLA protein (MGP), which binds excess calcium and prevents it from being deposited in blood vessels, promoting healthy blood flow and vessel elasticity .
Benefits of combining both Vitamin D3 and Vitamin K2
The following are the advantages of combining Vitamins D3 and K2.
- Promotes bone strength
- Promotes teeth strength
- Support normal immune system
- It can be used during pregnancy
- Protects blood vessel calcification
- Vitamin K2 supports normal blood clotting
For increased calcium in the bone
Simply increasing the amount of calcium that you consume will not be enough to ensure that your bones remain healthy. Did you know that besides calcium, you should also think about getting enough vitamin D and K2?
Both the absorption of calcium and the mineralization of bone are helped by vitamins D3 and K2, which also work to prevent arterial calcification. They help maintain a healthy cardiovascular system as well as healthy bones. Calcium is incapable of performing its function effectively in the absence of D3 and K2. While vitamin D3 helps maintain a healthy immune system and promotes healthy muscle function, vitamin K2 is responsible for regulating normal blood clotting [1,2,3].
For reduced calcium plaque in arteries
To bind excess calcium and to promote arterial flow and flexibility, the matrix GLA protein, also known as MGP, must first be activated by vitamin K2 (MK-7) .
In recent years, scientists have finally begun studying the potential immune-boosting effects of D3 and K2. There is accumulating evidence that higher levels of vitamin D can reduce the risk of COVID-19 infection … However, could the addition of K2 further improve health outcomes?
In a study published in March of this year, researchers sought to determine the relationship between vitamin D and K status and inflammatory response, elastic fiber degradation, and clinical outcomes in 135 hospitalized COVID-19 patients .
Vitamin D3 and K2 Benefits For Skin
One of the health benefits of Vitamin K2 is that it promotes skin health and helps maintain its elasticity, thereby preventing skin wrinkling.
By activating matrix GLA protein (MGP), vitamin K2 prevents calcium deposition in elastin fibers by absorbing excess calcium. In this way, calcium deposition during the aging and wrinkling process does not usually harden elastin fibers. Inadequate Vitamin K2 metabolism has also been linked to severe premature skin wrinkling .
Vitamin D3, however, has the following skin benefits:
- It reduces inflammation and treats psoriasis, eczema, and vitiligo.
- Vitamin D3 functions as a steroid and regulates the function of the cell nucleus to protect against cancer, particularly skin cancer.
- Vitamin D3 also functions as an antioxidant and can prevent environmental damage.
Vitamin D3 and K2 For Weight Loss
According to research, participants who were given a daily calcium and vitamin D supplement had a lower body mass index (BMI) than those who were given a placebo .
Studies have also shown that individuals with higher BMI and body fat had lower vitamin D blood levels . Before concluding whether vitamin D promotes weight loss, additional research is required.
In a clinical study, researchers also found that supplementation with Vitamin K promotes weight loss, particularly abdominal fat loss .
According to the National Institute of Health, the average adult who is not deficient in vitamin D, should consume 600 IU (International Units) per day. According to physicians, daily topical application of Vitamin D cream is safe .
For Vitamin D to function properly, anyone taking Vitamin D as a supplement should also take Vitamin K, but scientists have not yet recommended a daily dose of Vitamin K2.
Medical professionals, however, recommend a daily Vitamin K2 dosage of 1,000 micrograms or more for healthy adults to maintain normal body function. The majority of individuals consume greater amounts of vitamin K in their diets.
Vitamin D3 is generally considered safe when taken in moderate amounts; however, taking vitamin D3 over 4000 IU for an extended period of time is generally unsafe.
The amount of Vitamin K found in foods is also safe, but excessive consumption can have negative effects.
- Kidney failure
- Dry mouth
- Loss of appetite
- Mood changes, unusual tiredness
- Increased urination and increased thirst
Serious side effects of Vitamin K2 include:
- Nausea, heartburn, or stomach upset
- Severe stomach pain or vomiting
- Bloody diarrhea
Common and less serious side effects include:
- Constipation or diarrhea
- Mild nausea, heartburn, or stomach upset
- Loss of appetite or bad mouth taste
The Bottomline: Vitamin D3 and K2 Combination
Bone and cardiovascular health can benefit from adequate vitamin D3 and vitamin K2 intake. On the other hand, there is a need for further investigation into the functions of vitamins K2 and D3.
Many researchers believe that people who have a history of cardiovascular disease should make it a habit to take vitamin K2 supplements daily. Some people believe that more investigation must be carried out before sound recommendations can be made.
Despite this, it should be no surprise that vitamins K2 and D3 are necessary for proper bodily function.
Be sure to get adequate vitamin D3 and vitamin K2 through the foods you eat to keep your health in good standing.
Disclaimer: This article is only a guide. It does not substitute the advice given by your own healthcare professional. Before making any health-related decision, consult your healthcare professional.
Editorial References and Fact Checking
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